Lead DBS lead localization based on postoperative MRI

[eisinger]

Hello,
Are there any guides or further information on using Lead-DBS for lead localization based on a single postoperative MRI scan? I have successfully localized leads using preoperative MRI and postoperative CT, but I am trying to now complete the process solely with a postoperative MRI. What is the proper name for the nifti file of the postoperative mri that should be in the patient folder? I keep getting an error “Please put a suitable postoperative anatomy file inside the patient folder and normalize it first” on the pre-Reconstruct step.
Thanks,
Robert

[andreashorn]

Hi Robert,

you’d need a preop scan (call them anat_t1.nii and anat_t2.nii) and at least one postoperative MRI (postop_tra.nii) – call that one tra even if it’s sagittal. If you have multiple postop scans, you can call them postop_tra.nii, postop_cor.nii and postop_sag.nii

Now if you don’t have any baseline preop scan it’s hard to do it (given the lead artifacts will have a nonlinear impact on the normalization step). What you can do is to use the Linear Three-step protocol (but do make sure to read the associated schönecker paper so that you understand what really happens there).

If you want to try that, you’d make a duplicate of the single postop scan and call one copy postop_tra.nii, the other copy anat_t*.nii

best, Andy

[eisinger]

Thank you so much for the fast reply. Will test this out now. I did a quick search and came up with this dead url (http://www.andreas-horn.de/leaddbs/Lead_manual/book/Normalization%20of%20Images.html). Can you direct me to the paper you referred to? Thanks!

• This reply was modified 6 years, 8 months ago by eisinger.

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